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๐Ÿ“– Summaries โ€บ Zoology

Breathing and Exchange of Gases

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Breathing and Exchange of Gases

Cells use O2 to break down glucose, amino acids and fatty acids for energy, releasing harmful CO2. The exchange of O2 from the atmosphere with CO2 produced by the cells is called breathing (respiration).

Respiratory organs across animals

  • Sponges, coelenterates, flatworms: simple diffusion over the body surface.
  • Earthworms: moist cuticle.
  • Insects: network of tracheal tubes.
  • Aquatic arthropods and molluscs: gills (branchial respiration).
  • Terrestrial forms / fishes use gills; amphibians, reptiles, birds, mammals use lungs (pulmonary respiration). Frogs can also use moist skin (cutaneous respiration).

Human respiratory system

External nostrils -> nasal chamber -> pharynx -> larynx (sound box; epiglottis guards entry of food) -> trachea -> at the 5th thoracic vertebra divides into right and left primary bronchi -> secondary, tertiary bronchi -> bronchioles -> terminal bronchioles -> alveoli. The conducting part (nostrils to terminal bronchioles) transports, cleans, humidifies and warms air; the exchange part (alveoli and ducts) is the site of diffusion. Lungs lie in the air-tight thoracic chamber (dorsal vertebral column, ventral sternum, lateral ribs, lower diaphragm) and are covered by double-layered pleura.

Mechanism of breathing

  • Inspiration: contraction of diaphragm and external intercostals increases thoracic and pulmonary volume, lowering intra-pulmonary pressure below atmospheric pressure, so air moves in.
  • Expiration: relaxation of these muscles reduces volume, raising intra-pulmonary pressure above atmospheric pressure, so air moves out.
  • A healthy human breathes 12-16 times/minute; a spirometer measures lung volumes.

Respiratory volumes and capacities

TV (~500 mL), IRV (2500-3000 mL), ERV (1000-1100 mL), RV (1100-1200 mL). Derived capacities: IC = TV+IRV; EC = TV+ERV; FRC = ERV+RV; VC = ERV+TV+IRV; TLC = VC+RV.

Exchange and transport of gases

Gases diffuse based on partial pressure gradients. pO2: atmosphere 159, alveoli 104, deoxygenated blood 40, oxygenated blood 95, tissues 40 mm Hg. CO2 is 20-25 times more soluble than O2. About 97% of O2 travels as oxyhaemoglobin (sigmoid oxygen dissociation curve); CO2 travels ~70% as bicarbonate, 20-25% as carbamino-haemoglobin (via carbonic anhydrase), ~7% dissolved.

Regulation and disorders

The respiratory rhythm centre (medulla) is moderated by the pneumotaxic centre (pons) and a chemosensitive area sensitive to CO2 and H+; O2 plays an insignificant role. Disorders: asthma (inflammation of bronchi/bronchioles), emphysema (alveolar wall damage, mainly from smoking), and occupational disorders (dust-induced fibrosis).